What is the Difference Between Uptown and Downtown?

What's the difference between uptown and downtown?

"I'm going uptown to the bank"
"I'm going downtown for a drink"

Uptown: formal, business, etc. Downtown: informal, grittier, where all the action happens.

It definitely has more to do with the characteristics of certain parts of the city. Uptown tends to be he more "classier" part of town, where many people work and business is done. Where as Downtown seems to be the more "bustling" side of town, with nightclubs and tends to be where more people live.

Random, but I'm sure somebody will find this useful.